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Growth Hormone Secretagogue

MK-677 (Ibutamoren)

MK-677 (Ibutamoren) is a non-peptide agonist of the growth hormone secretagogue receptor subtype 1a (GHS-R1a). Binding to GHS-R1a activates Gq/11-mediated phospholipase C signaling, leading to IP3 and DAG generation, intracellular calcium mobilization, and downstream signaling cascade activation.…

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