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SARMs / Sold as SARMs (non-SARM)

Ibutamoren MK-677

MK-677 (Ibutamoren) is a non-peptide agonist of the growth hormone secretagogue receptor subtype 1a (GHS-R1a). Binding to GHS-R1a activates Gq/11-mediated phospholipase C signaling, leading to IP3 and DAG generation, intracellular calcium mobilization, and downstream signaling cascade activation. Research applications include receptor pharmacology, ligand-binding dynamics, signal transduction characterization, structure-activity relationship investigations, and comparative studies of GHS-R1a agonist activity.

Also known as MK-677, Nutrobal, ibutamoreno, GJ0EGN38UL, L 163191, L-163, 191, ibutamorenum, RefChem:55388, Ibutamoren [INN]

Routes Oral
Legal status Research chemical

3D Molecular Structure of C27H36N4O5S

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  • Carbon
  • Hydrogen
  • Nitrogen
  • Oxygen
  • Sulfur

Chemistry

Formula
C27H36N4O5S
Molar mass
528.7
CAS
159634-47-6
PubChem CID
178024
IUPAC name
2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
InChIKey
UMUPQWIGCOZEOY-JOCHJYFZSA-N